text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 115262-01-6 | Product Number: B4325


Purity: >98.0%(GC)
  • Bromodifluoro(trimethylsilyl)methane
2   ≥20 
1   ≥20 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).

Product Number B4325
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__4H__9BrF__2Si = 203.10  
Physical State (20 deg.C) Liquid
CAS RN 115262-01-6
Reaxys Registry Number 3535353
PubChem Substance ID 253659955
MDL Number


Appearance Colorless to Almost colorless clear liquid
Purity(GC) min. 98.0 %
Properties (reference)
Boiling Point 108 °C
Flash point 17 °C
Specific Gravity (20/20) 1.31
Refractive Index 1.41
Pictogram Pictogram
Signal Word Danger
Hazard Statements H225 : Highly flammable liquid and vapour.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P210 : Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 : Keep container tightly closed.
P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P403 + P235 : Store in a well-ventilated place. Keep cool.
Related Laws:
Transport Information:
UN Number UN1993
Class 3
Packing Group II
HS Number 2931900090
An Effective Precursor of a Difluorocarbene to Introduce Difluoromethylene Groups


Difluoromethylenation of alkynes: under a N2 atmosphere, alkynes (0.5 mmol, 1.0 eq.), (bromodifluoromethyl)trimethylsilane (152 mg, 0.75 mmol, 1.5 eq.), tetrabutylammonium bromide (4.8 mg, 0.015 mmol, 0.03 eq.), and toluene (2.0 mL) are added into an oven-dried pressure tube at room temperature. After being heated at 110 °C for 2 h, the reaction mixture is cooled to rt and poured into a saturated Na2CO3 solution (5 mL), followed by extraction with Et2O (2 × 15 mL). The organic layers are combined and dried over anhydrous K2CO3. After the removal of the solvents in vacuo, the residue is subjected to column chromatography (silica gel; petroleum ether : Et3N = 40 : 1) to afford the desired products. [Note: these products are sensitive to acid, so the column must be eluted previously with petroleum ether : Et3N = 10 : 1)].


PubMed Literature

Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Analytical Charts
Please enter Lot Number Incorrect Lot Number is entered

The requested analytical chart is not available. Sorry for the inconvenience.

Other Documents