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Published TCIMAIL newest issue No.199
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CAS RN: 117552-78-0 | Product Number: C2789
Calcium Dobesilate Hydrate
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Purity: >98.0%(HPLC)
Synonyms:
- Calcium 2,5-Dihydroxybenzenesulfonate Hydrate
- 2,5-Dihydroxybenzenesulfonic Acid Calcium Salt Hydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€86.00
|
1 | ≥80 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C2789 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__1__0CaO__1__0S__2·xH__2O = 418.40 (as Anhydrous) |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 117552-78-0 |
| Related CAS RN
|
20123-80-2 |
| Reaxys Registry Number | 3639290 |
| PubChem Substance ID | 253660116 |
| Merck Index (14) | 3394 |
| MDL Number | MFCD00867249 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Chelometric Titration) | min. 95.0 %(calcd.on anh.substance) |
| Water | 3.0 to 7.0 % |
| NMR | confirm to structure |
Properties (reference)
| Solubility in water | Soluble |
| Solubility (soluble in) | Alcohol |
| Solubility (insoluble in) | Chloroform, Benzene, Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 243-531-5 |
| RTECS# | DB6127000 |
Transport Information:
| HS Number | 2908990000 |
Application
Calcium Dobesilate: An Agent with Reported Antioxidant and Angioprotective Effects
It has been reported that calcium dobesilate possesses antioxidant and angioprotective effects in vitro, but its mechanisms of action are not elucidated. Calcium dobesilate is used in the treatment of diabetic retinopathy. (The product is for research purpose only.)
References
- Angioprotective action of calcium dobesilate against reactive oxygen species-induced capillary permeability in the rat
- Antioxidant properties of calcium dobesilate in ischemic/reperfused diabetic rat retina
- Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes
- Calcium dobesilate in the treatment of diabetic retinopathy (a review)
- Validation of liquid chromatographic method for analysis of lidocaine hydrochloride, dexamethasone acetate, calcium dobesilate, buthylhydroxyanisol and degradation product hydroquinone in suppositories and ointment
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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