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CAS RN: 24522-30-3 | Product Number: C3217
2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide
![Chemical Structure of 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide](/medias/C3217.jpg?context=bWFzdGVyfHJvb3R8Mzk5ODV8aW1hZ2UvanBlZ3xhRFkwTDJneE1DODRPVEl3T0RFNE5qUTNNRGN3TDBNek1qRTNMbXB3Wnd8ZDA1ODUxYTVkZmI5ZTI3YmIxOTcwZTVhN2M0MDkxOTYyOTE3MjQwMmFiMjU5M2UzODJmMzM0ZTAyYWI0MGJiMQ "2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide")
![Thumbnail of 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide](/medias/C3217.jpg?context=bWFzdGVyfHJvb3R8MTM2MjZ8aW1hZ2UvanBlZ3xhRGt6TDJneE55ODRPVE0wTWpNME9EUTVNekV3TDBNek1qRTNMbXB3Wnd8NTk2MmQ4MTAwZDMwMjU2ZjE5YmUzNzg1NjFkNjYwMzE5ZDg3NTkwYzMyNWY0NDgzNmU4Nzk0NDM4Nzk0OWQ3Mw)
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![2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide")
Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€ 102,00
|
1 | 2 |
|
|
| 5G |
€ 325,00
|
1 | 14 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3217 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__0H__7F__3N__2O = 228.17 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 24522-30-3 |
| Reaxys Registry Number | 2943267 |
| PubChem Substance ID | 354334210 |
| MDL Number | MFCD05669245 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 194.0 to 198.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 196 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
Transport Information:
| HS Number | 2926907090 |
Application
A Synthetic Intermediate of Dihydroorotate Dehydrogenase (DHO-DHase) Inhibitors
This product has been used as a synthetic intermediate of dihydroorotate dehydrogenase (DHO-DHase) inhibitors, such as teriflunomide [T3287] and leflunomide [L0250].
References
- Synthesis, Structure-Activity Relationships, and Pharmacokinetic Properties of Dihydroorotate Dehydrogenase Inhibitors: 2-Cyano-3-cyclopropyl-3-hydroxy-N-[3'-methyl-4'-(trifluoromethyl)phenyl]propenamide and Related Compounds
- 3-Hydroxy-2-cyanoalk-2-enamides, and 2-cyano-2-(tetrahydrofuran-2-ylidene)- and 2-cyano-2-(tetrahydropyran-2-ylidene)acetamides. Synthesis, structure, and solvent-dependent (Z)/(E)-isomerism
- Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application to in-vitro dissolution
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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