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CAS RN: 2140-67-2 | Product Number: D6076

N,N-Dimethylguanosine


Purity: >95.0%(HPLC)
Synonyms:
  • 2-Dimethylamino-6-oxypurine Riboside
  • 2-(Dimethylamino)guanosine
Documents:
25MG
€190.00
1   15  

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Product Number D6076
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__1__2H__1__7N__5O__5 = 311.30 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 2140-67-2
MDL Number

MFCD00057049

Specifications
Appearance White to Light yellow to Light orange powder to crystal
Water max. 1.0 %
Specific rotation -33.0 to -37.0 deg(C=0.1, 1M NaOHaq.)
Properties (reference)
Melting Point 239 °C(dec.)
GHS
Related Laws:
Transport Information:
HS Number 2934999090
Application
N,N-Dimethylguanosine: a modified ribonucleoside in tRNA and rRNA

N,N-Dimethylguanosine (N2,N2-dimethylguanosine, m22G) is a modified ribonucleoside that has long been known to present in tRNA and rRNA. Recent studies have discovered that N,N-dimethylguanosine is a prevalent RNA modification in eukaryotes and has roles in cell viability and development through these effects to RNA as follows; RNA stability and RNA structure.1-3) In addition, there are reports that the levels of modified nucleosides, including N,N-dimethylguanosine, have served as potential biomarkers for cancer and various diseases in many studies.4,5)

References


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