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CAS RN: 66852-54-8 | Product Number: H1457

Halobetasol Propionate

Purity: >98.0%(HPLC)
  • 21-Chloro-6α,9α-difluoro-11β,17α-dihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 17-Propionate
3   20  
1   16  

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Product Number H1457
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__5H__3__1ClF__2O__5 = 484.96 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 66852-54-8
Reaxys Registry Number 11109992
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Specific rotation [a]20/D +89.0 to +93.0 deg(C=1, Dioxane)
Properties (reference)
Melting Point 221 °C
Specific Rotation 91° (C=1,Dioxane)
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
RTECS# TU3723500
Transport Information:
HS Number 2937230000
Halobetasol propionate: A Super-Potent Corticosteroid

Halobetasol propionate is a super-potent corticosteroid with additional fluorine at the 6α position when compared with clobetasol 17-propionate [C2612]. The additional fluorine in the 6α position further increases its topical anti-inflammatory and antiproliferative activities. In addition, an ointment formulation in combination of halobetasol propionate and fusidic acid [F1007] for treatment of dermal conditions have been reported. (The product is for research purpose only.)


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