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CAS RN: 3420-72-2 | Product Number: H1571

Flavokawain A


Purity: >98.0%(GC)
Synonyms:
  • 2'-Hydroxy-4,4',6'-trimethoxychalcone
Documents:
1G
€50.00
3   2  
5G
€152.00
1   10  

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Product Number H1571
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__1__8H__1__8O__5 = 314.34  
Physical State (20 deg.C) Solid
CAS RN 3420-72-2
Related CAS RN 37951-13-6
Reaxys Registry Number 2009865
PubChem Substance ID 354334221
MDL Number

MFCD00017174

Specifications
Appearance Light yellow to Brown powder to crystal
Purity(GC) min. 98.0 %
Melting point 112.0 to 116.0 °C
Properties (reference)
Melting Point 114 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
Transport Information:
HS Number 2914500090
Application
Flavokawain A: An Apoptosis Inducing Agent

Flavokawain A, a major 2'-hydroxy-chalcone derived from kava plant extract, has recently demonstrated promising anti-cancer and anti-inflammatory activities. Some studies have shown that flavokawain A decreases cyclin-dependent kinase-2 (CDK2) inducing G2/M arrest in vitro, and then it has antiproliferative and apoptotic effects in cancer cells. In addition, it has been reported that flavokawain A suppresses expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). (The product is for research purpose only.)

References


PubMed Literature


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