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CAS RN: 155270-99-8 | Product Number: I1100


Purity: >98.0%(T)(HPLC)
  • (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione
1   ≥20 
1   ≥20 

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Product Number I1100
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__0H__2__4N__4O__4 = 384.44  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 155270-99-8
Reaxys Registry Number 7863436
MDL Number


Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Melting point 191.0 to 195.0 °C
Properties (reference)
Melting Point 193 °C
Maximum Absorption Wavelength 362(CH2Cl2) nm
Solubility in water Insoluble
Solubility (very slightly) Dimethylformamide,Ethanol
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# UO8414732
Transport Information:
HS Number 2933599590
Istradefylline: A Selective Adenosine A2A Receptor Antagonist

Istradefylline (KW-6002) is a selective adenosine A2A receptor antagonist. Adenosine A2A receptors are a G protein-coupled receptor (GPCR), and also one of the receptors of adenosine. In the brain, adenosine A2A receptors are considered to be present specifically in the basal ganglia, and are thought to be involved in the regulation of motor functions. The degeneration or abnormality observed in Parkinson's disease (PD) is believed to occur in the basal ganglia. Istradefylline as a high affinity and selectivity for A2A receptors. Reportedly, istradefylline has improved motor function in patients with advanced PD including loss of L-DOPA [D0600] efficacy. (The product is for research purpose only.)


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