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CAS RN: 100986-89-8 | Product Number: L0238
Levofloxacin Q-Acid
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€84.00
|
1 | ≥20 |
|
| 5G |
€270.00
|
1 | 10 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -62.0 to -64.0 deg(C=1、DMSO) |
Properties (reference)
| Specific Rotation | -64° (C=1,DMSO) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2934999090 |
Application
A Key Synthetic Intermediate of Levofloxacin and its Fluoromethyl Derivatives
This product is a key synthetic intermediate of levofloxacin [L0193] (optically active ofloxacin [O0403]) and its fluoromethyl derivativea which are fluoroquinolone antibiotics.
文献
- Synthesis and antibacterial activities of optically active ofloxacin
- Synthesis and antibacterial activities of optically active ofloxacin and its fluoromethyl derivative
- Chiral DNA gyrase inhibitors. 2. Asymmetric synthesis and biological activity of the enantiomers of 9-fluoro-3-methyl- 10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid (ofloxacin)
- A validated stability-indicating RP-HPLC method for levofloxacin in the presence of degradation products, its process related impurities and identification of oxidative degradant
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