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CAS RN: 555-57-7 | Product Number: M2618

Pargyline


Purity: >98.0%(GC)(T)
Synonyms:
  • N-Methyl-N-(2-propyn-1-yl)benzylamine
  • N-Methyl-N-propargylbenzylamine
Documents:
1G
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Product Number M2618
Purity / Analysis Method >98.0%(GC)(T)
Molecular Formula / Molecular Weight C__1__1H__1__3N = 159.23 
Physical State (20 deg.C) Liquid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive
CAS RN 555-57-7
Reaxys Registry Number 1938132
PubChem Substance ID 354333810
Merck Index (14) 7038
MDL Number

MFCD00008576

Specifications
Appearance Colorless to Light yellow to Light orange clear liquid
Purity(GC) min. 98.0 %
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Boiling Point 90 °C/4 mmHg
Flash point 84 °C
Specific Gravity (20/20) 0.95
Refractive Index 1.52
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
Related Laws:
EC Number 209-101-6
RTECS# DP6475000
Transport Information:
UN Number UN2810
Class 6.1
Packing Group III
HS Number 2921490090
Application
Pargyline: An Irreversible Selective MAO-B Inhibitor.

Monoamine oxidase B (MAO-B) is a mitochondrial outer membrane flavoenzyme, which keeps the norepinephrine concentration in the axoplasm low. Therefore, MAO-B is a well-known target for antidepressant and neuroprotective agents. Pargyline is an irreversible selective MAO-B inhibitor. Pargyline is used to treat moderate to severe hypertension. Currently, pargyline is used as an antiparkinson agent. (The product is for research purpose only.)

References


PubMed Literature


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