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CAS RN: 57113-90-3 | Product Number: M2797
Methyl 2-(tert-Butoxycarbonylamino)-3-nitrobenzoate
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Purity: >98.0%(GC)
Synonyms:
- 2-(tert-Butoxycarbonylamino)-3-nitrobenzoic Acid Methyl Ester
- Methyl 2-(Boc-amino)-3-nitrobenzoate
- 2-(Boc-amino)-3-nitrobenzoic Acid Methyl Ester
Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€86.00
|
1 | Contact Us |
|
| 25G |
€298.00
|
1 | 4 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Specifications
| Appearance | White to Yellow to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 104.0 to 108.0 °C |
Properties (reference)
| Melting Point | 106 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2924297099 |
Application
A Synthetic Intermediate of Azilsartan and Candesartan Cilexetil
This product is used for the synthesis of azilsartan [A2601]1,2) and candesartan cilexetil [C2635]2-4) which are angiotensin II type 1 receptor antagonist used mainly for the treatment of high blood pressure and congestive heart failure.
References
- An alternative synthesis of Azilsartan: an angiotensin II receptor blocker
- Synthesis and Characterization of Impurities of a Common and Advanced Intermediate of Candesartan and Azilsartan Antihypertensive Drugs
- Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of benzimidazolecarboxylic acids
- An efficient C-H arylation of a 5-phenyl-1H-tetrazole derivative: A practical synthesis of an angiotensin II receptor blocker
PubMed Literature
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