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CAS RN: 60-81-1 | Product Number: P0248

Phlorizin Hydrate


Purity: >97.0%(T)
Synonyms:
Documents:
1G
55,00 €
1   ≥20 
5G
181,00 €
5   19  

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Product Number P0248
Purity / Analysis Method >97.0%(T)
Molecular Formula / Molecular Weight C__2__1H__2__4O__1__0·xH__2O = 436.41  
Physical State (20 deg.C) Solid
CAS RN 60-81-1
Related CAS RN 7061-54-3
Reaxys Registry Number 66621
PubChem Substance ID 87574490
SDBS (AIST Spectral DB) 7601
Merck Index (14) 7327
MDL Number

MFCD00006591

Specifications
Appearance White to Light yellow to Light orange powder to crystal
Purity(Neutralization titration) min. 97.0 %(calcd.on anh.substance)
Specific rotation [a]20/D -52.0 to -55.0 deg(C=3.2, EtOH(95%))
Water max. 8.0 %
Properties (reference)
Specific Rotation -54° (C=3.2,EtOH(95vol%))
GHS
Related Laws:
EC Number 200-487-1
RTECS# UC2080000
Transport Information:
HS Number 2938909090
Application
Phlorizin: A Sodium Glucose Co-Transporter Inhibitor (SGLT)

Phlorizin is a 2'-O-glucoside of phloretin [P1966], first isolated from the bark of apple trees. Phlorizin’s principal pharmacological action is to reduce plasma glucose levels by blocking renal and intestinal glucose absorption through inhibition of sodium glucose co-transporters (SGLTs). Consequently, phlorizin has been used as a pharmaceutical tool for research of antidiabetic agent.

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