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CAS RN: 113-98-4 | Product Number: P1772

Penicillin G Potassium Salt


Purity: >98.0%(HPLC)(N)
Synonyms:
  • Benzylpenicillin Potassium Salt
Documents:
25G
35,00 €
4   ≥20 

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Product Number P1772
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__6H__1__7KN__2O__4S = 372.48  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
CAS RN 113-98-4
Related CAS RN 61-33-6
Reaxys Registry Number 3832841
PubChem Substance ID 87560525
Merck Index (14) 7094
MDL Number

MFCD00036193

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Specific rotation [a]20/D +270.0 to +300.0 deg(C=1, H2O)
Properties (reference)
Melting Point 217 °C(dec.)
Specific Rotation 294° (C=1,H2O)
Solubility in water Soluble
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P280 : Wear protective gloves.
P284 : Wear respiratory protection.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
Related Laws:
EC Number 204-038-0
RTECS# XH9700000
Transport Information:
HS Number 2941100000
Application
Penicillin G: The First Antibiotic belongs to Penicillins

Penicillin is the first antibiotic isolated from the mold Penicillium noctum, specifically it is known as penicillin G (other name: benzylpenicillin) and belongs to a class of similar antibiotics called penicillins. Nowadays penicillin G is produced by Penicillium chrysogenum fermentation. Penicillin G has activity against Gram-positive bacteria, but less activity against Gram-negative bacteria. It acts as a competitive inhibitor of the enzyme transpeptidase, which is needed by bacteria to make their cell walls. Meanwhile, β-lactamases (also called penicillinases) are enzymes produced by bacteria that deactivate penicillin G by destroying the β-lactam ring via hydrolysis. In rare cases, an allergy to penicillin G can cause an anaphylactic reaction, which can be deadly. Currently, the enzymatic hydrolysis of penicillin G gives 6-aminopenicillanic acid (6-APA) [A0800], which is a basic raw material for the industrial production of semisynthetic β-lactamase-resistant and broad spectrum penicillins such as amoxycillin [A2099] and ampicillin [A2092].

References


PubMed Literature


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