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CAS RN: 118292-40-3 | Product Number: T3108

Tazarotene

Chemical Structure of Tazarotene
×
× Tazarotene

Purity: >98.0%(GC)
Synonyms:
Product Documents:
SDS | Specifications | C of A & Other Certificates | Analytical Charts

General Information | Specifications & Properties | Safety & Regulations | Applications & Literature

Explanatory notes for this page

10MG
€28.00
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100MG
€178.00
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Product Number T3108
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__2__1H__2__1NO__2S = 351.46 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
CAS RN 118292-40-3
Reaxys Registry Number 8159145
PubChem Substance ID 253662270
Merck Index (14) 9081
MDL Number

MFCD00867628
Specifications
Appearance White to Yellow to Green powder to crystal
Purity(GC) min. 98.0 %
Melting point 102.0 to 106.0 °C
Properties (reference)
Melting Point 105 °C
GHS
Hazard Statements H413 : May cause long lasting harmful effects to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
Related Laws:
RTECS# US5675100
Transport Information:
HS Number 2934999090
Application
Tazarotene: A Synthetic Retinoic Acid Receptor (RAR)-β and γ Selective Retinoid

Retinoids exert their biological effects through two families of nuclear receptors, retinoic acid receptors (RARs) and retinoid X receptors (RXRs). RAR is a type of nuclear receptor which can also act as a transcription factor that is activated by both all-trans-retinoic acid [R0064] and 9-cis retinoic acid. There are three retinoic acid receptors (RAR-α, β, and γ). Tazarotene is a synthetic RAR-β and γ selective retinoid. Many studies have shown that tazarotene can affect cell proliferation and differentiation through upregulating the expression of tazarotene-induced genes TIG1, TIG2 and TIG3. Tazarotene is used for the treatment of plaque psoriasis and acne vulgaris. (The product is for research purpose only.)

References


PubMed Literature


Documents

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Safety Data Sheet (SDS)
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