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CAS RN: 99300-78-4 | Product Number: V0110

Venlafaxine Hydrochloride


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol Hydrochloride
Documents:
1G
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Product Number V0110
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__2__7NO__2·HCl = 313.87  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 99300-78-4
Related CAS RN 93413-69-5
Reaxys Registry Number 4240401
PubChem Substance ID 125307750
SDBS (AIST Spectral DB) 52922
Merck Index (14) 9946
MDL Number

MFCD03658865

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 217 °C
Solubility (soluble in) Methanol
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H370 : Causes damage to organs.
H372 : Causes damage to organs through prolonged or repeated exposure.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# QV8872760
Transport Information:
HS Number 2922500090
Application
Venlafaxine Hydrochloride: A Serotonin/Norepinephrine Reuptake Inhibitor (SNRI)

Venlafaxine hydrochloride belongs to a serotonin [S0370] /norepinephrine [A0906] reuptake inhibitors (SNRIs). Studies have shown that venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV) [D5598], are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak inhibitors of dopamine [A0305] reuptake. Venlafaxine and ODV have no significant affinity for muscarinic cholinergic, H1-histaminergic, or α1-adrenergic receptors in vitro. For your reference, duloxetine hydrochloride [D4223] and milnacipran hydrochloride [M2133] also belong to SNRIs. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
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