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CAS RN: 41621-49-2 | Product Number: C3545

Ciclopirox Olamine


Purity: >98.0%(HPLC)
Synonyms:
  • 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone Ethanolamine Salt
Documents:
1G
€75.00
3   ≥20 
5G
€225.00
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Product Number C3545
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__2H__1__7NO__2·C__2H__7NO = 268.36  
Physical State (20 deg.C) Solid
CAS RN 41621-49-2
Related CAS RN 29342-05-0
Reaxys Registry Number 6494273
Merck Index (14) 2266
MDL Number

MFCD00078997

Specifications
Appearance White to Almost white powder to crystaline
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 95.0 %
Properties (reference)
Melting Point 143 °C
Solubility (soluble in) Methanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws: / Compliance with laws, Regulations
Enzyme Commission 255-464-9
RTECS# UU7785500
Transport Information:
HS Number 2933790090
Application
Ciclopirox Olamine: An Antifungal Agent with Additional Antibacterial, Anti-Inflammatory and Antitumor Activities

Ciclopirox olamine is a synthetic, broad-spectrum antifungal agent with additional antibacterial, anti-inflammatory and also recently antitumor activities. In vitro studies have suggested that ciclopirox olamine acts by chelation of trivalent cations, such as Fe3+ and Al3+, resulting in the inhibition of the metal-dependent enzymes that are responsible for the cellular metabolism, organization of cell wall structure and other crucial cell functions.1,2) In addition, ciclopirox olamine exerts its anti-inflammatory activity by scavenging the reactive oxygen species (ROS) released from inflammatory cells.2) In 2000s, some studies have reported that ciclopirox olamine could be repositioned as a new antitumor agent.3-5) (The product is for research purpose only.)

References


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