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CAS RN: 30562-34-6 | Product Number: G0334


Purity: >98.0%(HPLC)
2   ≥20 

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Product Number G0334
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__9H__4__0N__2O__9 = 560.64  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 30562-34-6
Reaxys Registry Number 6835113
PubChem Substance ID 87560649
MDL Number


Appearance White to Yellow to Orange powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 4.75 to 5.25 %
Properties (reference)
Melting Point 255 °C
Maximum Absorption Wavelength 305(MeOH) nm
Solubility in water Practically insoluble
Solubility (soluble in) Chloroform,Methanol,Ethanol
Solubility (slightly sol. in) Benzene,Acetone
Related Laws: / Compliance with laws, Regulations
RTECS# LX8920000
Transport Information:
HS Number 2924297099
Studies on Geldanamycin as a Heat Shock Protein 90 (Hsp90) Inhibitor

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

C. E. Stebbins, A. A. Russo, C. Schneider, N. Rosen, F. U. Hartl, N. P. Pavletich, Cell 1997, 89, 239.

Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

S. M. Roe, C. Prodromou, R. O'Brien, J. E. Ladbury, P. W. Piper, L. H. Pearl, J. Med. Chem. 1999, 42, 260.

Geldanamycin as a potential anticancer agent: Its molecular target and biochemical activity

L. Neckers, T. W. Schulte, E. Mimnaugh, Invest. New Drugs 1999, 17, 361.

HSP90 as a new therapeutic target for cancer therapy: the story unfolds

A. Maloney, P. Workman, Expert Opin. Biol. Ther. 2002, 2, 3.

Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents

Y. Miyata, Curr. Pharm. Des. 2005, 11, 1131.

PubMed Literature

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