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CAS RN: 27848-84-6 | Product Number: N0904

Nicergoline


Purity: >98.0%(T)(HPLC)
Synonyms:
  • [(8R,10S)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl 5-Bromopyridine-3-carboxylate
  • 5-Bromopyridine-3-carboxylic Acid [(8R,10S)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl Ester
Documents:
100MG
€33.00
4   ≥20 
1G
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Product Number N0904
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__4H__2__6BrN__3O__3 = 484.39  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 27848-84-6
Reaxys Registry Number 903548
PubChem Substance ID 135727224
Merck Index (14) 9496
MDL Number

MFCD00869626

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 134.0 to 138.0 °C
Specific rotation [a]20/D +5.2 to +6.2 deg(C=5, EtOH(95vol%))
Properties (reference)
Melting Point 136 °C
Specific Rotation 6.0° (C=5,EtOH(95vol%))
Solubility (soluble in) Ethanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws: / Compliance with laws, Regulations
Enzyme Commission 248-694-6
RTECS# KE6341000
Transport Information:
HS Number 2933998090
Application
Pharmacological Studies
References

Nicergoline inhibits T-type calcium channels in rat isolated hippocampal CA1 pyramidal neurons

K. Takahashi, N. Akaike, Br. J. Pharmacol. 1990, 100, 705.

Modulation of hippocampal ACh release by chronic nicergoline treatment in freely moving young and aged

N. Carfagna, A. D. Clemente, S. Cavanus, D. Damiani, M. Gerna, P. Salmoiraghi, B. Cattaneo, C. Post, Neurosci.

Cholinergic deficits in aged rat brain are corrected with nicergoline

N. Ogawa, M. Asanuma, H. Hirata, Y. Kondo, Y. Kawada, A. Mori, Arch. Gerontology Geriatrics, 1993, 16, 103.

Pharmacological study of nicergoline. Effects on regional cerebral blood flows and arterial carbon dioxide and oxygen pressure and pH in rats under cyanide-induced histotoxic anoxia

K. Shintomi, Arzneim.-Forsch. 1991, 41, 885.


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