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CAS RN: 125-33-7 | Product Number: P1906

Primidone


Purity: >98.0%(HPLC)(N)
Synonyms:
  • 5-Ethyl-5-phenylhexahydropyrimidine-4,6-dione
  • 2-Deoxyphenobarbital
Documents:
5G
€27.00
3   ≥20 
25G
€74.00
1   11  

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*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number P1906
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__2H__1__4N__2O__2 = 218.26  
Physical State (20 deg.C) Solid
CAS RN 125-33-7
Reaxys Registry Number 218034
PubChem Substance ID 125307742
Merck Index (14) 7746
MDL Number

MFCD00038662

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Properties (reference)
Melting Point 281 °C
Solubility in water Insoluble
Solubility (soluble in) Dimethylformamide
Solubility (very slightly) Ethanol
Solubility (insoluble in) Ether
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H351 : Suspected of causing cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
Related Laws: / Compliance with laws, Regulations
Enzyme Commission 204-737-0
RTECS# UV9100000
Transport Information:
HS Number 2933790090
Application
Pharmacology study
References

Blood and cerebrospinal fluid pharmacokinetics of primidone and its primary pharmacologically active metabolites, phenobarbital and phenylethylmalonamide in the rat

S. Nagaki, N. Ratnaraj, P. N. Patsalos, Eur. J. Drug Metab. Pharmacokinetics 1999, 24, 255.

Pharmacological characterization of harmaline-induced tremor activity in mice

N. E. Paterson, S. A. Malekiani, M. M. Foreman, B. Olivier, T. Hanania, Eur. J. Pharmacol. 2009, 616, 73.

Primidone

H. H. Frey, Handb. Exp. Pharmacol. 1985, 74, 449.


PubMed Literature


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