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CAS RN: 60-82-2 | Product Number: P1966

Phloretin


Purity: >98.0%(HPLC)
Synonyms:
  • 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
  • 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)propiophenone
Documents:
1G
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5G
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Product Number P1966
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__5H__1__4O__5 = 274.27  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 60-82-2
Reaxys Registry Number 1887240
PubChem Substance ID 135727056
Merck Index (14) 7326
MDL Number

MFCD00002288

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 95.0 %
Properties (reference)
Melting Point 262 °C(dec.)
Solubility in water Insoluble
Solubility (very soluble in) Acetone,Alcohol
Solubility (very slightly) Chloroform,Benzene
Solubility (insoluble in) Ether
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws: / Compliance with laws, Regulations
Enzyme Commission 200-488-7
Transport Information:
HS Number 2914500090
Application
Phloretin: A Dihydrochalcone with Many Interesting Biological Properties

Phloretin is a dihydrochalcone and a polyphenol, can be found in apple tree leaves. Phloretin and its glycosylated derivative (phlorizin [P0248]) have many interesting biological properties. For example, phloretin inhibits sodium glucose co-transporters (SGLTs), though the inhibition is weaker than by phlorizin. In addition, phloretin shows an antioxidant activity in peroxynitrite scavenging and the inhibition of lipid peroxidation.

References


PubMed Literature


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