CAS RN: 19545-26-7 | Product Number: W0007
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|Purity / Analysis Method||>98.0%(HPLC)|
|Molecular Formula / Molecular Weight||C__2__3H__2__4O__8 = 428.44|
|Physical State (20 deg.C)||Solid|
|Condition to Avoid||Light Sensitive,Heat Sensitive|
|Reaxys Registry Number||67676|
|PubChem Substance ID||253659701|
|Merck Index (14)||10053|
|Appearance||White to Yellow powder to crystal|
|Purity(HPLC)||min. 98.0 area%|
|Melting point||235.0 to 239.0 °C|
|Specific rotation||+85.0 to +89.0 deg(C=0.17,CHCl3)|
|Melting Point||237 °C|
|Maximum Absorption Wavelength||296 nm|
|Hazard Statements||H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled.
|Precautionary Statements||P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P262 : Do not get in eyes, on skin, or on clothing.
P280 : Wear protective gloves/ protective clothing.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes.
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-triphosphate in neutrophil responses
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine
Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
1)Historical landmarks of autophagy research
2)Autophagy: renovation of cells and tissues
3)Regulation of autophagy by kinases
4)Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
5)Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
6)Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses
7)The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
8)Variation in the safety of induced pluripotent stem cell lines
9)PI3K/AKT signaling pathway is essential for survival of induced pluripotent stem cells
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