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Published TCIMAIL newest issue No.199
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CAS RN: 13241-33-3 | Product Number: N1121
Neohesperidin
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Purity: >97.0%(HPLC)
Synonyms:
- (2S)-7-[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyloxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
- Hesperetin 7-O-Neohesperidoside
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
€121.00
|
2 | 19 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N1121 |
Purity / Analysis Method 
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__8H__3__4O__1__5 = 610.57 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 13241-33-3 |
| PubChem Substance ID | 354335519 |
| MDL Number | MFCD16661259 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Melting point | 237.0 to 244.0 °C |
Properties (reference)
| Melting Point | 243 °C |
| Specific Rotation | -97° (C=1,Pyridine) |
GHS
Related Laws:
| EC Number | 236-216-9 |
| RTECS# | DJ2981400 |
Transport Information:
| HS Number | 2938909090 |
Application
Quorum sensing research / Biofilm research
References
- Inhibition of Quorum Sensing (QS) in Yersinia enterocolitica by an Orange Extract Rich in Glycosylated Flavanones
- Suppression of bacterial cell–cell signalling, biofilm formation and type III secretion system by citrus flavonoids
Application
抗酸化作用を有する柑橘系フラバノン，ネオヘスペリジン
The citrus flavanones neohesperidin, hesperidin [H0049], hesperetin [H0721] and naringin [N0073] are known to exhibit antioxidant activities and could cross the blood-brain barrier, and they reportedly have neuroprotective effects against reactive oxygen species (ROS).1-4) In addition, neohesperidin is an important starting compound for the synthesis of neohesperidin dihydrochalcone [N0675] which is a non-nutritive sweetening agent.5) (The product is for research purpose only.)
References
- 1)Antioxidant Activity of Citrus Limonoids, Flavonoids, and Coumarins
- 2)Juice components and antioxidant capacity of citrus varieties cultivated in China
- 3)Flavanones in citrus fruit: Structure-antioxidant activity relationships
- 4)Neuroprotective Effects of the Citrus Flavanones against H2O2-Induced Cytotoxicity in PC12 Cells
- 5)Selection of citrus varieties highly productive for the neohesperidin dihydrochalcone precursor
- 6)Flavanones in oranges, tangerines (mandarins), tangors, and tangelos: a compilation and review of the data from the analytical literature (a review)
- 7)Flavonones in grapefruit, lemons, and limes: A compilation and review of the data from the analytical literature (a review)
PubMed Literature
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