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Published TCIMAIL newest issue No.198
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CAS RN: 745-65-3 | Product Number: P1917
Prostaglandin E1
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Purity: >98.0%(HPLC)
Synonyms:
- Alprostadil
- PGE1
- (11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-13-en-1-oic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 10MG |
€179.00
|
2 | 7 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P1917 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__4O__5 = 354.49 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 745-65-3 |
| Reaxys Registry Number | 2061617 |
| PubChem Substance ID | 468592574 |
| Merck Index (14) | 7875 |
| MDL Number | MFCD00077860 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 115.0 to 119.0 °C |
| Specific rotation | -64.0 to -68.0 deg(C=0.2,ethanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 116 °C |
| Maximum Absorption Wavelength | 278 nm (EtOH) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 212-017-2 |
| RTECS# | GY4569800 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2937500000 |
Application
Prostaglandin E1: A Naturally Occurring Prostaglandin with Vasodilation and Anti-Platelet Aggregating Effects
Prostaglandin E1 (PGE1) is produced by the theoretical metabolism of dihomo-y-linolenic acid (DGLA) [E0640] by the cyclooxygenase pathway.1) It has been reported that PGE1 has many pharmacological activities, such as vasodilation, anti-inflammatory, anti-platelet aggregation, protection of vascular endothelial cells, prevention of atherosclerosis, and so on.2) PGE1 is known to improve fluidity of blood through its vasodilation and anti-platelet aggregating effects. (The product is for research purpose only.)
References
- 1) Pharmacokinetics of prostaglandin E1 and its main metabolites after intracavernous injection and short-term infusion of prostaglandin E1 in patients with erectile dysfunction
- 2) The rationale for prostaglandin E1 in erectile failure: A survey of worldwide experience (a review)
Documents
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