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Published TCIMAIL newest issue No.198
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CAS RN: 119302-91-9 | Product Number: R0099
Rocuronium Bromide
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Purity: >90.0%(T)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
€83.00
|
4 | 19 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | R0099 |
Purity / Analysis Method 
|
>90.0%(T) |
| Molecular Formula / Molecular Weight | C__3__2H__5__3BrN__2O__4 = 609.69 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 119302-91-9 |
| Related CAS RN
|
143558-00-3 |
| Reaxys Registry Number | 7161858 |
| PubChem Substance ID | 253659588 |
| Merck Index (14) | 8246 |
| MDL Number | MFCD00867768 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC)(CAD) | min. 90.0 area% |
| Purity(Nonaqueous Titration) | min. 90.0 % |
| Specific rotation [a]20/D | +28.5 to +32.0 deg(C=1, 0.05mol/L HCl)(calcd.on anh.substance) |
| Water | max. 6.0 % |
Properties (reference)
| Melting Point | 169 °C |
| Specific Rotation | 30° (C=1,0.05mol/L HCl) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
Related Laws:
Transport Information:
| HS Number | 2934999090 |
Application
Rocuronium Bromide: A Nicotinic Acetylcholine Receptor Antagonist
Rocuronium bromide is a muscle relaxant in the category of non-depolarizing blocking agents. Rocuronium bromide has antagonistic properties that target the neuromuscular nicotinic acetylcholine receptor, and has a shorter time of onset of action than vecuronium bromide [V0120]. (The product is for research purpose only.)
References
- Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969
- Rocuronium: The newest aminosteroid neuromuscular blocking drug
- Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors
- Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey
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