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CAS RN: | Product Number: A2510

Anti-Lewis Y Monoclonal Antibody


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Product Number A2510
Physical State (20 deg.C) Liquid
Storage Temperature -80°C
Condition to Avoid Heat Sensitive
Specifications
Appearance Colorless to Almost colorless clear liquid
Titer(ELISA) to pass test
Properties (reference)
GHS
Related Laws: / Compliance with laws, Regulations
Transport Information:
HS Number 3002150000
Application
Anti-Lewis Y Monoclonal Antibody
References

High idiotypic connectivity of the VH7183-encoded antibodies directed to a murine embryonic carbohydrate antigen, Lewis Y, as ascertained by syngenic anti-idiotype monoclonal antibodies.

K. Hirashima, K. Zenita, A. Takada, A. Kitahara, G. Ishihara, R. Harada, K. Ohmori, S. Hirohashi, S. Kyoizumi, M. Akiyama, R. Kannagi, J. Immunol. 1990, 145, 224-232.

Preparation of mouse-human chimeric antibody to an embryonic carbohydrate antigen, Lewis Y.

T. Kaneko, Y. Iba, K. Zenita, K. Shigeta, K. Nakano, W. Itoh, Y. Kurosawa, R. Kannagi, K. Yasukawa, J. Biochem. 1993, 113, 114-117.

Targeted gene transfer for adenocarcinoma using a combination of tumor-specific antibody and tissue-specific promoter.

S. Kurane, J. C. Krauss, E. Watari, R. Kannagi, A. E. Chang, S. Kudoh, Jpn. J. Cancer Res. 1998, 89, 1212-1219.

Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-Lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin.

S. Mathieu, M. Prorok, A.-M. Benoliel, R. Uch, C. Langlet, P. Bongrand, R. Gerolami, A. El-Battari, Am. J. Pathol. 2004, 164, 371-383.

Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.

H. Hotta, K. Hamamura, K. Yamashita, H. Shibuya, N. Tokuda, N. Hashimoto, K. Furukawa, N. Yamamoto, H. Hattori, S. Toyokuni, M. Ueda, K. Furukawa, Glycoconj. J. 2013, 30, 585-597.

Reactivities of Lewis antigen monoclonal antibodies with the lipopolysaccharides of Helicobacter pylori strains isolated from patients with gastroduodenal diseases in Japan.

K. Amano, S. Hayashi, T. Kubota, N. Fujii, S. Yokota, Clin. Diagn. Lab. Immunol. 1997, 4, 540-544.

Developmental changes in the biochemical and immunological characters of the carbohydrate moiety of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan.

T. Shuo, S. Aono, F. Matsui, Y. Tokita, H. Maeda, K. Shimada, A. Oohira, Glycoconj. J. 2004, 20, 267-278.

Detection of ligands for selectins in the oligosaccharide fraction of human milk.

S. Rudloff, C. Stefan, G. Pohlentz, C. Kunz, Eur. J. Nutr. 2002, 41, 85-92.

Expression of glycolipids bearing Lewis phenotypes in tissues and cultured cells of human gynecological cancers.

K. Takehara, K. Kubushiro, K. Kiguchi, I. Ishiwata, K. Tsukazaki, S. Nozawa, M. Iwamori, Jpn. J. Cancer Res. 2002, 93, 1129-1137.


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