Netilmicin Sulfate: An Aminoglycoside Antibiotic with Less Ear and Kidney Toxicity
Netilmicin sulfate, a semisynthetic 1-
N-ethyl derivative of sisomicin sulfate [
I1049], is an aminoglycoside antibiotic with action similar to gentamicin sulfate [
G0383], but less ear and kidney toxicity. Netilmicin is active against most Gram-negative and Gram-positive
Staphylococcus, including many gentamicin-resistant strains. Netilmicin interacts with the 30S subunit of bacterial ribosomes, and then it inhibits bacterial growth by inhibiting protein synthesis.
(The product is for research purpose only.)