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Published TCIMAIL newest issue No.201
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CAS RN: 17321-77-6 | Product Number: C3897
Clomipramine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 3-[3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl]-N,N-dimethyl-1-propanamine Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
44,00 €
|
Contact Us | 12 |
|
|
| 5G |
106,00 €
|
1 | 18 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3897 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__3ClN__2·HCl = 351.32 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic |
| CAS RN | 17321-77-6 |
| Reaxys Registry Number | 4168494 |
| MDL Number | MFCD00069234 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Precipitation Titration) | min. 98.0 % |
| Melting point | 191.0 to 195.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 193 °C |
| Degree of solubility in water | 250 g/l 20 °C |
| Solubility (soluble in) | Ethanol |
| Solubility (insoluble in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. |
Related Laws:
Transport Information:
| HS Number | 2933998090 |
Application
Clomipramine: A Selective Serotonin Reuptake Inhibitor
Clomipramine hydrochloride is a selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitor and is used as a tricyclic antidepressant in clinical. (The product is for research purpose only.)
Reference
- Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder
- Clinical pharmacokinetics of clomipramine (a review)
- Optimised procedures for the reversed-phase liquid chromatographic analysis of formulations containing tricyclic antidepressants
- Optimization and validation of spectrofluorimetric method for the determination of clomipramine hydrochloride via ion-pair complexation with alizarin red S
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