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Published TCIMAIL newest issue No.201
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CAS RN: 130209-82-4 | Product Number: L0262
Latanoprost
Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
Supplemental Product Information:
Due to the limited filling volume, some of the product may stick to the inner walls of the bottle.
| Product Number | L0262 |
Purity / Analysis Method
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__4__0O__5 = 432.60 |
| Physical State (20 deg.C) | Liquid |
Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 130209-82-4 |
| Reaxys Registry Number | 5912370 |
| PubChem Substance ID | 253662165 |
| Merck Index (14) | 5376 |
| MDL Number | MFCD00216074 |
Specifications
| Appearance | Colorless to Light yellow clear liquid |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +33.0 to +36.0 deg(C=1, CHCl3) |
Properties (reference)
| Flash point | 188 °C |
| Specific Rotation | 34° (C=1,CHCl3) |
| Solubility in water | Insoluble |
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
| RTECS# | MJ9669550 |
Transport Information:
| HS Number | 2937500000 |
Application
Latanoprost: A Selective Prostanoid FP Receptor Agonist
Latanoprost, a phenyl-substituted prostaglandin F2α (PGF2α) analog, is a selective prostanoid FP receptor agonist. It reduces the intraocular pressure (IOP) in both animal and human subjects mainly by enhancing uveoscleral outflow. (The product is for research purpose only.)
References
- Prostaglandin F2α and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species
- Effect of latanoprost on the extracellular matrix of the ciliary muscle. A study on cultured cells and tissue sections
- Microvascular effects of selective prostaglandin analogues in the eye with special reference to latanoprost and glaucoma treatment (a review)
- A review of the use of Latanoprost for glaucoma since its launch
PubMed Literature
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Specifications
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