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Published TCIMAIL newest issue No.201
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CAS RN: 54-95-5 | Product Number: P0046
1,5-Pentamethylenetetrazole
Purity: >98.0%(GC)
Synonyms:
- Cardiazole
Product Documents:
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| Product Number | P0046 |
Purity / Analysis Method
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__6H__1__0N__4 = 138.17 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 54-95-5 |
| Reaxys Registry Number | 135492 |
| PubChem Substance ID | 87574318 |
| SDBS (AIST Spectral DB) | 10356 |
| Merck Index (14) | 7141 |
| MDL Number | MFCD00005939 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 59.0 to 63.0 °C |
| Solubility in Water | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 60 °C |
| Boiling Point | 194 °C/12 mmHg |
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 200-219-3 |
| RTECS# | XF8225000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933998090 |
Application
Reagents convulsion or paralysis model
References
- Studies on prostaglandin F2 alpha formation caused by pentametylenetetrazol-induced convulsions in rat brain
- AP-1 and CRE DNA binding activities in rat brain following pentylenetetrazole induced seizures
- A neuropharmacological analysis of PTZ-induced kindling in mice
- Upregulation of NMDA receptors in hippocampus and cortex in the pentylenetetrazol-induced "kindling" model of epilepsy
- Effects of compounds acting on GABA(B) receptors in the pentylenetetrazole kindling model of epilepsy in mice
- Changes in AMPA receptor binding and subunit messenger RNA expression in hippocampus and cortex in the pentylenetetrazole-induced 'kindling' model of epilepsy
- Interactions of tiagabine with ethosuximide in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves
- Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves
- J. J. Luszczki, M. Krzyzanowski, M. J. Swiader, Adv. Med. Sci. 2009, 54, 75
- Effect of ACEA--a selective cannabinoid CB1 receptor agonist on the protective action of different antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model
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