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CAS RN: 497-76-7 | Product Number: A0522


Purity: >95.0%(HPLC)
  • Hydroquinone-β-D-glucoside
  • 4-Hydroxyphenyl β-D-Glucopyranoside
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Product Number A0522
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__1__2H__1__6O__7 = 272.25 
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Hygroscopic
CAS RN 497-76-7
Reaxys Registry Number 89673
PubChem Substance ID 87562130
SDBS (AIST Spectral DB) 10908
Merck Index (14) 773
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 95.0 area%
Melting point 197.0 to 202.0 °C
Specific rotation [a]20/D -63.0 to -68.0 deg(C=4, H2O)(calcd.on anh.substance)
Solubility in Water very faint turbidity
Water max. 3.0 %
Properties (reference)
Melting Point 198 °C
Specific Rotation -65.5° (C=4,H2O)
Solubility in water Soluble
Solubility (soluble in) Alcohol
Related Laws:
EC Number 207-850-3
RTECS# CE8863000
Transport Information:
HS Number 2938909090
Arbutin: A Competitive Inhibitor of Tyrosinase

Arbutin (β-arbutin) is a hydroquinone glycoside, which is accumulated in many plant species such as bearberry (Arctostaphylos uva-ursi L.), bergenia (Bergenia spp.) and myrothamnus (Myrothamnus flabellifolia Welw.). It has been reported that arbutine inhibits the oxidation of L-tyrosine in a competitive manner catalyzed by tyrosinase which is an oxidase that catalyzes the rate-limiting step in melanin (a group of natural pigments) biosynthesis. Arbutins (α- and β-arbutins) are widely used in the cosmetic industry. (Related product: α-arbutin [A3284]) (The product is for research purpose only.)


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