CAS RN: 665-66-7 | Product Number: A0588
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
|Appearance||White to Almost white powder to crystal|
|Purity(Nonaqueous Titration)||min. 99.0 %|
|Purity(Argentmetric Titration)||min. 99.0 %|
|Solubility in Water||almost transparency|
|Melting Point||360 °C|
|Hazard Statements||H302 : Harmful if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
|Precautionary Statements||P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
These mechanisms of action are not fully understood. However, there is evidence to suggest that 1-adamantanamine act as a dopamine receptor agonist by enhancing the synthesis and release of dopamine from nerve cells and delaying the reuptake into synaptic vesicles.2,3)
In addition, 1-adamantanamine inhibits the replication of influenza A viruses by preventing the release of infectious viral RNA into the host cell nucleus by interfering with the function of the transmembrane of the viral M2 protein.4,5) (The product is for research purpose only.)
- 1)Amantadine: The journey from fighting flu to treating Parkinson disease (a review)
- 2)Amantadine (a review)
- 3)Renaissance of amantadine in the treatment of Parkinson's disease (a review)
- 4)Influenza virus M2 protein has ion channel activity
- 5)Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
- 6)Amantadine (a review on the nomenclature, synthesis, reactions, stability, physical properties, and methods of detection)
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