text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 665-66-7 | Product Number: A0588

1-Adamantanamine Hydrochloride


Purity: >99.0%(T)
Synonyms:
  • 1-Aminoadamantane Hydrochloride
  • Amantadine Hydrochloride
  • 1-Adamantylamine Hydrochloride
Documents:
25G
£32.00
4   Contact Us
250G
£155.00
Contact Us 3  

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Note:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number A0588
Purity / Analysis Method >99.0%(T)
Molecular Formula / Molecular Weight C__1__0H__1__7N·HCl = 187.71  
Physical State (20 deg.C) Solid
CAS RN 665-66-7
Related CAS RN 768-94-5
Reaxys Registry Number 4198854
PubChem Substance ID 87562172
MDL Number

MFCD00074723

Specifications
Appearance White to Almost white powder to crystal
Purity(Nonaqueous Titration) min. 99.0 %
Purity(Argentmetric Titration) min. 99.0 %
Solubility in Water almost transparency
Properties (reference)
Melting Point 360 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
EC Number 211-560-2
RTECS# AU4375000
Transport Information:
HS Number 2921309990
Application
1-Adamantanamine Hydrochloride: A Dopamine Receptor Agonist and an Anti-Influenza A Virus Agent

1-Adamantanamine hydrochloride and its free base [A2318] are dopamine receptor agonists and anti-influenza A virus agents, similarly rimantadine hydrochloride [R0070]. 1-Amantadine was originally developed as an antiviral agent. One day, a single patient noticed relief in her Parkinson’s disease symptoms after taking amantadine for a flu infection, and this observation led to a new drug indication.1)
These mechanisms of action are not fully understood. However, there is evidence to suggest that 1-adamantanamine act as a dopamine receptor agonist by enhancing the synthesis and release of dopamine from nerve cells and delaying the reuptake into synaptic vesicles.2,3)
In addition, 1-adamantanamine inhibits the replication of influenza A viruses by preventing the release of infectious viral RNA into the host cell nucleus by interfering with the function of the transmembrane of the viral M2 protein.4,5) (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Documents
Safety Data Sheet (SDS) Search
Please select Language.

The requested SDS is not available.

• Please check that the Product Number you have entered is correct.

• If your information is correct and you are still not able to view the requested SDS,  please Contact Us for more information.

C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Other Documents