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CAS RN: | Product Number: A2701

Anti-GalNAc-GD1a Monoclonal Antibody


Purity:
Synonyms:
Documents:
1VIAL
£245.00
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Note:

Product Information
Volume/Quantity:0.1 mg/vial
Product Form:Purified mouse monoclonal antibody/IgM, κ-chain
Buffer:Phosphate buffered-saline(-) (PBS(-))
Preparation:The antibody is purified from mouse ascites fluid.
Preservative:0.05% sodium azide
Stabilizer:None
Immunogen: Salmonella minnesota strain R595 coated with ganglioside mixture from human hepatocellular carcinoma cells, PLC/PRF/5
Specificity:Ganglioside GalNAc-GD1a. This antibody recognizes terminal GalNAcβ1→4(NeuAcα2→3)Galβ-R structure, and reacts to GM2, GalNAc-sialyl-nLc4, and Cad-active glycoproteins.
Clone Name:2A3D2

Applications
Immunohistochemistry
ELISA
Western blotting
TLC-immunostaining

Storage
Store in freezer (-20ºC to -80ºC). It is not recommended storing at 4ºC. Avoid repeated freezing and thawing.

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Product Number A2701
Physical State (20 deg.C) Liquid
Storage Temperature -80°C
Condition to Avoid Heat Sensitive
Specifications
Appearance Colorless to Almost colorless clear liquid
Titer(ELISA) to pass test
Properties (reference)
GHS
Related Laws:
Transport Information:
HS Number 3002150000
Application
Anti-GalNAc-GD1a Monoclonal Antibody
References

Gangliosides and sialoglycoproteins carrying a rare blood group antigen determinant, Cad, associated with human cancers as detected by specific monoclonal antibodies

N. Hiraiwa, K. Tsuyuoka, Y.-T. Li, M. Tanaka, T. Seno, Y. Okubo, Y. Fukuda, H. Imura, R. Kannagi, Cancer Res. 1990, 50, 5497.

Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages

K. Zenita, K. Hirashima, K. Shigeta, N. Hiraiwa, A. Takada, K. Hashimoto, E. Fujimoto, K. Yago, R. Kannagi, J. Immunol. 1990, 144, 4442.

Localization of UDP-GalNAc:NeuAcα-2,3Gal-Rβ-1,4(GalNAc to Gal)N- acetylgalactosaminyltransferase in human stomach. Enzymatic synthesis of a fundic gland-specific ganglioside and GM2

T. Dohi, N. Hanai, K. Yamaguchi, M. Oshima, J. Biol. Chem. 1991, 266, 24038.

Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines

T. Dohi, M.Nakasuji, M. Oshima, Int. J. Cancer. 1993, 53, 137.

A guide to monoclonal antibodies directed to glycotopes

R. Kannagi, S. Hakomori, Adv. Exp. Med. Biol. 2001, 491, 587.

Red blood cell antigens responsible for inherited types of polyagglutination

E. Lisowska, M. Duk, Adv. Exp. Med. Biol. 2001, 491, 141.


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