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CAS RN: 154229-19-3 | Product Number: A2868

Abiraterone


Purity: >98.0%(HPLC)
Synonyms:
  • 17-(3-Pyridyl)androsta-5,16-dien-3β-ol
Documents:
20MG
£24.00
3   5  
200MG
£97.00
1   3  

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number A2868
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__4H__3__1NO = 349.52  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 154229-19-3
Reaxys Registry Number 7309269
PubChem Substance ID 253661112
MDL Number

MFCD00924100

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 97.0 %
Melting point 226.0 to 230.0 °C
Properties (reference)
Melting Point 228 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
H373 : May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
Related Laws: / Compliance with laws, Regulations
Transport Information:
HS Number 2933399990
Application
Abiraterone: A Selective Inhibitor of the Steroidogenic Enzyme Cytochrome P450 17A1 (CYP17A1)

Abiraterone is a selective inhibitor of the steroidogenic enzyme cytochrome P450 17A1 (CYP17A1) which catalyzes two key serial reactions (17α-hydroxylase hydroxylase and 17,20-lyase) in androgen and estrogen biosynthesis. Abiraterone acetate [A2891] (of which the active metabolite is abiraterone) is an agent used in combination with prednisone [P1276] in metastatic castration-resistant prostate cancer (mCRPC). (The product is for research purpose only.)

References


PubMed Literature


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