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CAS RN: 199875-69-9 | Product Number: A3446

N-Arachidonoyl Dopamine


Purity: >98.0%(HPLC)
Synonyms:
  • NADA
  • (5Z,8Z,11Z,14Z)-N -[2-(3,4-Dihydroxyphenyl)ethyl]-5,8,11,14-eicosatetraenamide
  • (5Z,8Z,11Z,14Z)-N-(3,4-Dihydroxyphenethyl)icosa-5,8,11,14-tetraenamide
Documents:
10MG
£114.00
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Product Number A3446
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__8H__4__1NO__3 = 439.64 
Physical State (20 deg.C) Liquid
Storage Temperature -20°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Air Sensitive,Heat Sensitive
CAS RN 199875-69-9
Reaxys Registry Number 7779367
MDL Number

MFCD03412031

Specifications
Appearance Colorless to Yellow clear liquid
Purity(HPLC)(CAD) min. 98.0 area%
NMR confirm to structure
Properties (reference)
Flash point 341 °C
GHS
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Transport Information:
Application
N-Arachidonoyldopamine: An Endogenous Cannabinoid

N-Arachidonoyldopamine (NADA) is was first synthesized as a pharmacological tool to study the endogenous cannabinoid system (ECS).1) Later NADA and other N-acyldopamines were identified as endogenous cannabinoids in the mammalian nervous tissue.2,3) It has been reported that NADA acts as an agonist of the cannabinoid 1 (CB1) receptors.1-3) It is selective for CB1 over CB2 receptors. Furthermore, NADA also acts as an agonist of the transient receptor potential vanilloid type 1 (TRPV1) ion channel, also known as the capsaicin receptor.2,3) For your reference, the endogenous cannabinoid system (ECS) modulates neuronal and immune cell function, both of which play key roles in pain, therapeutics targeting this system hold promise as novel analgesics.3) (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
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