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CAS RN: 31677-93-7 | Product Number: B3649

Bupropion Hydrochloride

Purity: >98.0%(T)(HPLC)
  • 2-(tert-Butylamino)-1-(3-chlorophenyl)-1-propanone Hydrochloride
  • Amfebutamone Hydrochloride
1   ≥20 
1   ≥20 

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Product Number B3649
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__3H__1__8ClNO·HCl = 276.20  
Physical State (20 deg.C) Solid
CAS RN 31677-93-7
Related CAS RN 34911-55-2
Reaxys Registry Number 6161273
PubChem Substance ID 125307968
SDBS (AIST Spectral DB) 52948
Merck Index (14) 1499
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 222 °C
Solubility (soluble in) Methanol
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
EC Number 250-759-9
RTECS# UG8858000
Transport Information:
HS Number 2922390090
Bupropion Hydrochloride: a Dopamine-Norepinephrine Reuptake Inhibitor and a Nicotinic Antagonist

Bupropion hydrochloride is presumed to be a norepinephrine-dopamine reuptake inhibitor (NDRI) and a nicotinic antagonist. Bupropion is metabolized in liver by cytochrome P 450 2B6 (CYP2B6) to hydroxybupropions which are believed to contribute to antidepressant and perhaps smoking cessation activities.


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