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CAS RN: 155206-00-1 | Product Number: B6165

Bimatoprost


Purity: >98.0%(HPLC)
Synonyms:
  • (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide
  • 17-Phenyltrinor-PGF2α Ethylamide
Documents:
5MG
£90.00
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25MG
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Product Number B6165
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__5H__3__7NO__4 = 415.57 
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 155206-00-1
Reaxys Registry Number 9365461
PubChem Substance ID 468590953
Merck Index (14) 1221
MDL Number

MFCD03411999

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Melting point 72.0 to 76.0 °C
Specific rotation [a]20/D +34.2 to +37.8 deg(C=1, MeOH)
Properties (reference)
Melting Point 75 °C
Specific Rotation 35° (C=1,MeOH)
Solubility (soluble in) Ethanol, Methanol
Solubility (slightly sol. in) Dimethylformamide
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# MJ8808000
Transport Information:
HS Number 2937500000
Application
Bimatoprost: A Synthetic Prostaglandin F (PGF) Analog with Unique Ocular Hypotensive Activity

Bimatoprost (AGN 192024) is a synthetic prostaglandin F (PGF) analog having pharmacological and biochemical properties district from PGF. PGF is formed from the endocannabinoid anandamide by a biosynthetic pathway involving cyclooxygenase-2 (COX-2). However, bimatoprost selectively mimics the effects of naturally occurring substances, prostamides. The target receptor for bimatoprost and the prostamides appears unique and unrelated to PG- and endocannabinoid-sensitive receptors. Although its mechanism of action is not completely understood, bimatoprost is believed to lower intraocular pressure (IOP) in humans by increasing outflow aqueous humor through both the trabecular meshwork and uveoscleral routes. In clinical, bimatoprost is used for the treatment of glaucoma. (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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