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CAS RN: 298-46-4 | Product Number: C1095

Carbamazepin


Purity: >97.0%(N)
Synonyms:
  • 5H-Dibenzo[b,f]azepine-5-carboxamide
  • Carbamazepine
Documents:
10G
£42.00
1   ≥20 
25G
£56.00
4   ≥20 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number C1095
Purity / Analysis Method >97.0%(N)
Molecular Formula / Molecular Weight C__1__5H__1__2N__2O = 236.27  
Physical State (20 deg.C) Solid
CAS RN 298-46-4
Reaxys Registry Number 1246090
PubChem Substance ID 87566126
SDBS (AIST Spectral DB) 16056
Merck Index (14) 1781
MDL Number

MFCD00005073

Specifications
Appearance White to Almost white powder to crystal
Purity(with Total Nitrogen) min. 97.0 %
Melting point 188.0 to 193.0 °C
Solubility in Methanol within very faint turbidity
Properties (reference)
Melting Point 191 °C
Solubility in water Insoluble
Solubility (soluble in) Acetone,Dimethylformamide,Chloroform,Methanol
Solubility (slightly sol. in) Ethanol
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H373 : May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P314 : Get medical advice/ attention if you feel unwell.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
EC Number 206-062-7
RTECS# HN8225000
Transport Information:
HS Number 2933998090
Application
Carbamazepine: A Nerve Stabilizer

Carbamazepine (carbamazepin) stabilizes hyper excited nerve membranes, inhibits repetitive neuronal discharges, and reduces synaptic propagation of excitatory impulses. Although, the mechanisms of action of carbamazepine are not completely understood, but it has been reported that carbamazepine prevents the repetitive firing of sodium-dependent action potentials in depolarized neurons via voltage-dependent blockade of sodium channels. Recent studies shows that carbamazepine-induced Stevens-Johnson syndrome is associated with a gene polymorphism of Human leukocyte antigen, HLA-B*1502. On the other hand, the removal of carbamazepine is a problem in the wastewater treatment plants. (The product is for research purpose only.)

References


PubMed Literature


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