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Published TCIMAIL newest issue No.199
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CAS RN: 72558-82-8 | Product Number: C2225
Ceftazidime (contains ca. 10% Na2CO3)
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Purity:
Synonyms:
- CAZ (contains ca. 10% Na2CO3)
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
£57.00
|
9 | ≥100 |
|
|
| 25G |
£180.00
|
5 | 16 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C2225 |
| Molecular Formula / Molecular Weight | C__2__2H__2__2N__6O__7S__2 = 546.57 |
| Physical State (20 deg.C) | Solid |
Storage Temperature 
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 72558-82-8 |
| Reaxys Registry Number | 4344904 |
| PubChem Substance ID | 87560561 |
| Merck Index (14) | 1946 |
| MDL Number | MFCD00072034 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -22.0 to -26.0 deg(C=0.5, pH6.0 Phosphate Buffer) |
| Drying loss | max. 14.0 % |
| Ignition residue(Sulfate) | 10.0 to 15.0 % |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P280 : Wear protective gloves. P284 : Wear respiratory protection. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 276-715-9 |
| RTECS# | UU2225000 |
Transport Information:
| HS Number | 2941900000 |
Application
Ceftazidime: A Third Generation Semisynthetic Cephalosporin Antibiotic with Activity against Pseudomonas aeruginosa
Ceftazidime is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form
7-aminocephalosporanic acid (7-ACA) [A1266]. It has broad spectrum activity against Gram-positive and Gram-negative bacteria, however has weaker activity against Gram-positive bacteria. Furthermore, it is different from other cephalosporins by virtue of its activity against Pseudomonas aeruginosa.
7-aminocephalosporanic acid (7-ACA) [A1266]. It has broad spectrum activity against Gram-positive and Gram-negative bacteria, however has weaker activity against Gram-positive bacteria. Furthermore, it is different from other cephalosporins by virtue of its activity against Pseudomonas aeruginosa.
References
- The Activity of Ceftazidime Compared with Those of Aztreonam, Newer Cephalosporins and Sch 29482 against Nonfermentative Gram-Negative Bacilli
- Ceftazidime (an update of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy)
- In-vitro comparative study of Cefoperazone, Ceftazidime, Ceftizoxime, Cefotaxime, Ceftriaxone and Cefixime against Pseudomonas aeruginosa
- Ceftazidime-Avibactam: a Novel Cephalosporin/β-lactamase Inhibitor Combination
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