text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 50-63-5 | Product Number: C2301

Chloroquine Diphosphate


Purity: >98.0%(T)(HPLC)
Synonyms:
  • N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate
  • 7-Chloro-4-[4-(diethylamino)-1-methylbutylamino]quinoline Diphosphate
Documents:
25G
£29.00
4   13  
100G
£99.00
1   ≥40 
500G
£348.00
2   6  

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Note:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number C2301
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__8H__2__6ClN__3·2H__3PO__4 = 515.86 
Physical State (20 deg.C) Solid
CAS RN 50-63-5
Reaxys Registry Number 4223142
PubChem Substance ID 87560990
SDBS (AIST Spectral DB) 52374
Merck Index (14) 2163
MDL Number

MFCD00069852

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 199 °C(dec.)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
EC Number 200-055-2
RTECS# VB2450000
Transport Information:
HS Number 2933499090
Application
Exosome research

References


Application
Chloroquine Diphosphate: A Derivative of 4-Aminoquinoline with Autophagy Inhibitory, Antimalarial and Anticancer Activities

Chloroquine diphosphate is a derivative of 4-aminoquinoline, which is an inhibitor of autophagy and has antimalarial and anticancer activities.1-3) In addition, chloroquine has been also reported to exert anti-corona viral activity, including anti-SARS-CoV-2, in vitro.4-6) The mechanism of action of chloroquine is not completely understood. But, some studies have demonstrated that chloroquine is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. In addition, while chloroquine can inhibit certain enzymes, its effect is believed to result, at least in part from its interaction with DNA. (The product is for research purpose only.)

References


Application
Reagent for itching model

Reference


PubMed Literature


TCIMAIL
Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Analytical Charts
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The requested analytical chart is not available. Sorry for the inconvenience.

Other Documents

Session Status
Your session will timeout in 10 minutes. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page. minute. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page.

Your session has timed out. You will be redirected to the HOME page.