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CAS RN: 132203-70-4 | Product Number: C2564

Cilnidipine


Purity: >98.0%(HPLC)
Synonyms:
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl Ester
  • 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
Documents:
1G
£38.00
1   ≥20 
5G
£108.00
1   16  

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Product Number C2564
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__7H__2__8N__2O__7 = 492.53  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 132203-70-4
Reaxys Registry Number 9093961
PubChem Substance ID 135727151
Merck Index (14) 2275
MDL Number

MFCD00865853

Specifications
Appearance Light orange to Yellow to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 5.55 to 5.75 %
Melting point 108.0 to 112.0 °C
Properties (reference)
Melting Point 110 °C
GHS
Related Laws:
RTECS# US7975550
Transport Information:
HS Number 2933399990
Application
Cilnidipine: A Long-Acting Dual Antagonist of L-Type and N-Type Ca2+ Channels

Cilnidipine (FRC-8653), a dihydropyridine derivative, is a long-acting dual antagonist of L-type Ca2+ channels in vascular smooth muscle and N-type Ca2+ channels in sympathetic nerve terminals that supply blood vessels. Cilnidipine dilates blood vessels by L-type Ca2+ channel antagonism in the vascular smooth muscles, and consequently lower blood pressure. Cilnidipine also inhibits elevation of heart rate and blood pressure under stress by N-type Ca2+ channel antagonism in the sympathetic nerve. (The product is for research purpose only.)

References


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