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CAS RN: 168555-66-6 | Product Number: C3009

Combretastatin A4 Phosphate Disodium Salt


Purity: >98.0%(HPLC)
Synonyms:
  • Fosbretabulin Disodium Salt
Documents:
20MG
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100MG
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Product Number C3009
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__8H__1__9Na__2O__8P = 440.30 
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 168555-66-6
PubChem Substance ID 354333373
MDL Number

MFCD00943911

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Properties (reference)
GHS
Related Laws:
Transport Information:
HS Number 2919900090
Application
Antitumor Compound, Combretastatin A4 Phosphate (CA4P)

Combretastatin A4 phosphate (CA4P), a water-soluble antitumor prodrug of Combretastatin A4, is converted to Combretastatin A4 by metabolism. CA4P inhibits microtubule polymerization, thereby inducing mitotic arrest and apoptosis in endothelial cells. It has been reported that CA4P has significant effects on tumor vascularization by disrupting vascular endothelial cadherin.

References


PubMed Literature


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