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Published TCIMAIL newest issue No.199
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CAS RN: 530-43-8 | Product Number: C3258
Chloramphenicol Palmitate
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Purity: >97.0%(T)(HPLC)
Synonyms:
- D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol Palmitate
- 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)-2-propyl]acetamide Palmitate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
£17.00
|
Contact Us | ≥40 |
|
|
| 1G |
£57.00
|
1 | ≥60 |
|
|
| 5G |
£187.00
|
1 | ≥60 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3258 |
Purity / Analysis Method 
|
>97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__4__2Cl__2N__2O__6 = 561.54 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 530-43-8 |
| Reaxys Registry Number | 2826438 |
| PubChem Substance ID | 354333644 |
| Merck Index (14) | 2077 |
| MDL Number | MFCD00083597 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Argentometric Titration) | min. 97.0 % |
| Melting point | 91.0 to 96.0 °C |
| Specific rotation [a]20/D | +20.5 to +25.4 deg(C=2, EtOH(99.5)) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 94 °C |
| Specific Rotation | 24° (C=2,EtOH(99.5)) |
| Maximum Absorption Wavelength | 271 nm (EtOH) |
| Solubility in water | Slightly soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| EC Number | 208-477-9 |
| RTECS# | RT4735000 |
Transport Information:
| HS Number | 2941400000 |
Application
Chloramphenicol Palmitate: A Prodrug of Chloramphenicol
Chloramphenicol palmitate is a poorly water-soluble prodrug of chloramphenicol [C2255] for oral administration as a suspension agnent. The palmitate ester is inactive, requiring hydrolysis to chloramphenicol for anti-bacterial activity. The palmitate ester is hydrolyzed in the small intestine to active chloramphenicol prior to absorption. (The product is for research purpose only.)
References
- Clinical pharmacokinetics of chloramphenicol and chloramphenicol succinate
PubMed Literature
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