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CAS RN: 70356-03-5 | Product Number: C3478

Cefaclor Monohydrate


Purity: >98.0%(T)(HPLC)
Synonyms:
Documents:
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Product Number C3478
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__5H__1__4ClN__3O__4S·H__2O = 385.82  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 70356-03-5
Merck Index (14) 1912
MDL Number

MFCD00071999

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D +100 to +115 deg(C=0.4, water)
Water 4.5 to 5.5 %
Properties (reference)
Specific Rotation 110° (C=0.4,H2O)
Solubility in water Soluble
Solubility (insoluble in) Benzene,Chloroform,Methanol
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P280 : Wear protective gloves.
P284 : Wear respiratory protection.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
Related Laws:
RTECS# XI0365000
Transport Information:
HS Number 2941900000
Application
Cefaclor: A Second Generation Semisynthetic Cephalosporin Antibiotics with 3-Chloro Group

Cefaclor is a second generation semisynthetic cephalosporin antibiotics which possesses a chemical structure substituted with chloro group for the 3-methyl group present in cephalexin [C2248] molecule. Cefaclor is active against a wide range of commonly encountered bacterial pathogens, acting by inhibiting cell wall synthesis. The antibiotic activities against Gram-positive and Gram-negative bacterial pathogens are several times more than that of cephalexin.

References


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