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CAS RN: 305-01-1 | Product Number: E0386


Purity: >98.0%(T)(HPLC)
  • 6,7-Dihydroxycoumarin
3   ≥40 

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Product Number E0386
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__9H__6O__4 = 178.14 
Physical State (20 deg.C) Solid
CAS RN 305-01-1
Reaxys Registry Number 152788
PubChem Substance ID 87569645
SDBS (AIST Spectral DB) 23227
Merck Index (14) 3697
MDL Number


Appearance Light yellow to Brown to Dark green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 273 °C
Maximum Absorption Wavelength 344(MeOH) nm
Solubility (insoluble in) Ether
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
EC Number 206-161-5
RTECS# GN6382500
Transport Information:
HS Number 2932209090
Esculetin: The Main Active Ingredient of the Traditional Chinese Medicine Cortex Fraxini

Esculetin is the main active ingredient of the traditional Chinese medicine Cortex Fraxini with antioxidant properties. Esculetin has shown its various pharmacological effects, including anti-inflammatory, anticoagulant, antioxidant, liver-protective, antidiabetic, antibacterial and antitumor effects. Some reports suggests that esculetin exerts inhibitory effect on lipoxygenase and cell cycle, but the mechanisms of its action are not completely understood. (The product is for research purpose only.)


PubMed Literature


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