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CAS RN: 162359-56-0 | Product Number: F1018

Fingolimod Hydrochloride


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-Amino-2-[2-(4-n-octylphenyl)ethyl]propane-1,3-diol Hydrochloride
  • FTY 720
Documents:
200MG
£39.00
1   ≥20 
1G
£134.00
1   ≥20 

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Product Number F1018
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__9H__3__3NO__2·HCl = 343.94  
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Condition to Avoid Heat Sensitive
CAS RN 162359-56-0
Related CAS RN 162359-55-9
Reaxys Registry Number 7837310
PubChem Substance ID 253660828
Merck Index (14) 4083
MDL Number

MFCD00939512

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 110 °C
Solubility in water Completely soluble
Solubility (very soluble in) Ethanol,Methanol
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
Related Laws: / Compliance with laws, Regulations
RTECS# TY3130000
Transport Information:
HS Number 2922190090
Application
Fingolimod hydrochloride (FTY720): An Immunomodulatory Agent Working as a Sphingosine 1-Phosphate Receptor Agonist

Fingolimod was first synthesized in 1992 by chemical modification of an immunosuppressive natural product, myriocin which is a metabolite of the fungus. Fingolimod hydrochloride (FTY720) is an orally active immunomodulatory agent, and inhibits lymphocyte emigration from lymphoid organs. Recent data show that FTY720 is a prodrug, and phosphorylated FTY720 is an agonist at sphingosine 1-phosphate (S1P) receptors. FTY720 is commonly used for the treatment of multiple sclerosis, an inflammatory disorder of the central nervous system. (The product is for research purpose only.)

References


PubMed Literature


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