CAS RN: 21187-98-4 | Product Number: G0381
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|Appearance||White to Almost white powder to crystal|
|Purity(HPLC)||min. 98.5 area%|
|Purity(Neutralization titration)||min. 98.5 %|
|Melting point||165.0 to 169.0 °C|
|Melting Point||167 °C|
|Solubility in water||Insoluble|
|Solubility (soluble in)||Dimethylformamide|
|Solubility (slightly sol. in)||Methanol,Ethanol|
- Gliclazide. An update of its pharmacological properties and therapeutic efficacy in non-insulin-dependent diabetes mellitus (a review)
- Sulfonylurea stimulation of insulin secretion (a review)
- Gliclazide modified release (a review)
- Improvement of water solubility and in vitro dissolution rate of gliclazide by complexation with β-cyclodextrin
- Enhancement of dissolution rate of gliclazide using solid dispersions with polyethylene glycol 6000
- Cogrinding as an approach to enhance dissolution rate of a poorly water-soluble drug (gliclazide)
- The development and validation of liquid chromatography method for the simultaneous determination of metformin and glipizide, gliclazide, glibenclamide, or glimperide in plasma
- The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated potassium channel in insulin-secreting cells
- H. Schmid-Antomarchi, L. De Weille, M. Fosset, M. Lazdunski, J. Biol. Chem. 1987, 262, 15840.
- Antidiabetic sulfonylureas control action potential properties in heart cells via high affinity receptors that are linked to ATP-dependent potassium channels
- M. Fosset, J. R. De Weille, R. D. Green, H. Schmid-Antomarchi, M. Lazdunski, J. Biol. Chem. 1988, 263, 7933.
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