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CAS RN: 10238-21-8 | Product Number: G0382


Purity: >98.5%(T)(HPLC)
  • 5-Chloro-N-[4-(3-cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
  • Glyburide
Contact Us ≥20 
3   ≥20 

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Product Number G0382
Purity / Analysis Method >98.5%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__3H__2__8ClN__3O__5S = 494.00  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 10238-21-8
Reaxys Registry Number 2230085
PubChem Substance ID 135726994
Merck Index (14) 4478
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.5 area%
Purity(Neutralization titration) min. 98.5 %
Melting point 172.0 to 176.0 °C
Properties (reference)
Melting Point 174 °C
Solubility in water Insoluble
Solubility (soluble in) Dimethylformamide
Solubility (slightly sol. in) Ethanol,Methanol
Related Laws:
EC Number 233-570-6
RTECS# YS4725200
Transport Information:
HS Number 2924210090
Glibenclamide: A Sulfonylurea ATP-Dependent K+ Channel Antagonist

Glibenclamide belongs to sulfonylurea antidiabetics which increase the release of insulin from pancreatic B-cells. Sulfonylurea antidiabetics inhibit ATP-gated K+ channels and thereby cause depolarization of the B-cell membrane. The depolarization leads to activation of voltage-dependent Ca channels and Ca2+ influx into the B-cell, and eventually increases insulin release. Recently, a combination agent with metformin [M2009] is also used for the treatment of Type 2 diabetes. (The product is for research purpose only.)


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