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CAS RN: 65646-68-6 | Product Number: H1464


Purity: >98.0%(HPLC)
  • 4-HPR
  • Fenretinide
  • Retinoic Acid p-Hydroxyanilide
1   7  
1   2  

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Product Number H1464
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__6H__3__3NO__2 = 391.56 
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 65646-68-6
Reaxys Registry Number 5769490
PubChem Substance ID 253662215
Merck Index (14) 3998
MDL Number


Appearance White to Yellow to Orange powder to crystal
Purity(HPLC) min. 98.0 area%
Melting point 170.0 to 174.0 °C
Properties (reference)
Melting Point 172 °C
Maximum Absorption Wavelength 362(MeOH) nm
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H360 : May damage fertility or the unborn child.
Precautionary Statements P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell.
Related Laws:
RTECS# VH6420000
Transport Information:
HS Number 2924297099
4-HPR: A Retinoid Analog with Antitumor Activities

all-trans-N-(4-hydroxyphenyl)-retinamide (4-HPR) is a synthetic retinoid analog that not only inhibits the proliferation of cancer cells but also can induces apoptosis in certain cancer cells. Recent studies have shown that 4-HPR has additional properties including the prevention of high-fat diet-induced obesity and insulin resistance. The mechanism of action of 4-HPR is still not fully understood.


PubMed Literature

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