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CAS RN: 85801-02-1 | Product Number: I0943

Indometacin Farnesil


Purity: >98.0%(HPLC)
Synonyms:
Documents:
25MG
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100MG
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Product Number I0943
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__3__4H__4__0ClNO__4 = 562.15  
Physical State (20 deg.C) Liquid
CAS RN 85801-02-1
PubChem Substance ID 354333527
MDL Number

MFCD00870661

Specifications
Appearance Light yellow to Yellow to Orange clear liquid
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 2.00 to 3.00 %
Properties (reference)
Flash point 333 °C
Solubility in water Insoluble
Solubility (very soluble in) Ethanol,Chloroform,Ether,Acetone
Solubility (slightly sol. in) Methanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# NL3522820
Transport Information:
HS Number 2933998090
Application
Indometacin Farnesil: A Prodrug of the Non-Steroidal Anti-Inflammatory Drug Indomethacin

Indometacin farnesil is a prodrug of the non-steroidal anti-inflammatory drug (NSAID) indomethacin [I0655], designed to reduce the occurrence of side-effects in the gastrointestinal tract. When indometacin farnesil is administered orally, it is absorbed through the gastrointestinal tract as unchanged drug which is mildly injurious to the tract. Indometacin farnesil is metabolized to indomethacin, the active form, in the liver and kidney, and this indomethacin inhibits prostaglandin biosynthesis by inhibiting cyclooxygenase (COX). (The product is for research purpose only.)

References


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