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CAS RN: 123663-49-0 | Product Number: I0945

Iguratimod


Purity: >98.0%(T)(HPLC)
Synonyms:
  • N-[7-(Methanesulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl]formamide
  • N-(3-Formamido-4-oxo-6-phenoxy-4H-chromen-7-yl)methanesulfonamide
Documents:
25MG
£25.00
1   14  
250MG
£150.00
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Product Number I0945
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__1__4N__2O__6S = 374.37  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
CAS RN 123663-49-0
Reaxys Registry Number 8640145
PubChem Substance ID 253660421
MDL Number

MFCD00882374

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 238.0 to 242.0 °C
Properties (reference)
Melting Point 240 °C
Solubility in water Insoluble
Solubility (insoluble in) Ethanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws: / Compliance with laws, Regulations
Transport Information:
HS Number 2935909099
Application
Iguratimod (T-614): An Agent with Anti-Inflammatory and Immunomodulatory Activities

Iguratimod (T-614) is an agent with anti-inflammatory and immunomodulatory activities. Iguratimod inhibits the production of immune globulin and inflammatory cytokines such as TNF-α, IL-1β and IL-6 in vitro. Even though the mechanism of action of iguratimod is still not fully understood, the suppression of nuclear factor kappa B (NF-κB) activation has been indicated. Iguratimod is used as a disease modifying anti-rheumatic drug (DMARD). (The product is for research purpose only.)

References


PubMed Literature


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