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CAS RN: 434-13-9 | Product Number: L0089

Lithocholic Acid


Purity: >98.0%(T)
Synonyms:
  • 5β-Cholanic Acid-3α-ol
  • 3α-Hydroxy-5β-cholanic Acid
Documents:
5G
£40.00
3   ≥20 
25G
£180.00
2   ≥20 

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*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number L0089
Purity / Analysis Method >98.0%(T)
Molecular Formula / Molecular Weight C__2__4H__4__0O__3 = 376.58  
Physical State (20 deg.C) Solid
CAS RN 434-13-9
Reaxys Registry Number 3217757
PubChem Substance ID 87572051
SDBS (AIST Spectral DB) 10707
Merck Index (14) 5545
MDL Number

MFCD00003682

Specifications
Appearance White to Almost white powder to crystaline
Purity(GC) min. 97.0 %
Purity(Neutralization titration) min. 98.0 %
Melting point 185.0 to 190.0 °C
Specific rotation [a]20/D +33.0 to +38.0 deg(C=1, EtOH)
Properties (reference)
Melting Point 186 °C
Specific Rotation 35.5° (C=1,EtOH)
Solubility in water Insoluble
Degree of solubility in water 0.38 mg/l   25 °C
Solubility (slightly sol. in) Ethanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
EC Number 207-099-1
RTECS# FZ2275000
Transport Information:
HS Number 2918199890
Application
Lithocholic acid: A Monohydroxy Secondary Bile Acid

Lithocholic acid is a monohydroxy secondary bile acid that acts as a detergent to solubilize fats for absorption. It is formed in the colon by bacterial 7-dehydroxylation of the primary bile acid chenodeoxycholic acid (CDCA) [C0750] and of the secondary bile acid ursodeoxycholic acid (UDCA) [U0030]. Recently, lithocholic acid is identified as an endogenous ligand of the vitamin D receptor (VDR) and a pregnane X receptor (PXR) activator. Lithocholic acid has been used for several therapeutic purposes in man. (The product is for research purpose only.)

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